产品资讯| 双链RNA结合蛋白Staufen抗体
 

　　别 名：Double stranded RNA binding protein Staufen homolog 1; Double stranded RNA binding protein Staufen homolog; Double-stranded RNA-binding protein Staufen homolog 1; Double-stranded RNA-binding protein Staufen homolog; FLJ25010; MGC124588; STAU; STAU1; STAU1_HUMAN; staufen; Staufen RNA binding protein (Drosophila); Staufen RNA binding protein homolog 1.

　　研究领域：免疫学 神经生物学 细胞骨架 细胞外基质

　　抗体来源：Rabbit

　　克隆类型：Polyclonal

　　交叉反应：Human, Mouse, Rat, (predicted: Chicken, Cow, Horse, )

　　产品应用：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

　　分 子 量：63, 126kDa

　　细胞定位：细胞浆

　　性 状：Liquid

　　浓 度：1mg/ml

　　免 疫 原：KLH conjugated synthetic peptide derived from human Staufen/STAU1:421-520/577

　　亚 型：IgG

　　纯化方法：affinity purified by Protein A

　　储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

　　保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

　　PubMed：PubMed

　　产品介绍：STAU1 (staufen, RNA binding protein, homolog 1) is a 577 amino acid protein that contains three double-stranded RNA-binding domains and is a mammalian homolog of Staufen, a Drosophila protein that is involved in mRNA transport during oogenesis and zygotic development. Localized to the rough endoplasmic reticulum (RER) and expressed in a variety of tissues, including heart, brain, liver, lung, pancreas, kidney and placenta, STAU1 binds to both Tubulin and double-stranded RNA and is thought to play an important role in mRNA transport from the microtubule network to the RER. Additionally, STAU1 may be involved in cross-linking cytoskeletal components with RNA, an event that is important for proper mRNA positioning during translation. Alternative splicing of the STAU1 gene yields two STAU1 isoforms, designated short and long.

　　Function: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.

　　双链RNA结合蛋白Staufen抗体上海古朵生物科技有限公司成立于上海浦东新区。是一家专门从事生物技术相关产品，励志研发和销售的综合性生物公司，产品远销多个国家和地区，我们将一如既往地秉承“一切为了满足客户的需求"的经营宗旨;牢固树立“以客户需求为准则、以市场需求为导向，不断开发高质量的新产品，提供客户满意的综合服务质量"的方针。古朵试剂盒